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<title>Bioinformatic Sequence Comparison Game Directions</title>
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  <div class="content">
    <h1>How To Play</h1>
    
    <ol>
    	<li><a href="#players">Players</a></li>
		<li><a href="#cards">Cards</a></li>
		<li><a href="#play">How to Play</a></li>
		<li><a href="#score">Scoring</a></li>
		<li><a href="#end">End Game</a></li>
		<li><a href="#credits">Credits</a></li>
	</ol>
    
    <h2 id="players">Players</h2>
    <p>
    	The game can be played by 1-4 players.
    </p>
    
    
    <h2 id="cards">Cards</h2>
    <p>
    	The deck is comprised of 102 cards, represented by 20 amino acids.  Each card shows its amino acid's single and three-letter 
        abbreviations along with its molecular structure as shown here:
        <p><img src="images/card_expl.gif" width="396" height="326" alt="card descriptions" /></p>
         The following table shows the amino acids in the deck, their chemical characteristics,
    abbreviated names, and their occurrence in the deck.</p>
    <p><img src="images/card_descriptions.jpg" width="594" height="543" alt="card descriptions" /></p>
    
    <h2 id="play">How to Play</h2>
    <p>
    	The game board consists of the deck, discard pile, and the player(s) hands. Each player is dealt cards, face down, at the beginning of the game and one card is placed face up to start the discard pile.    
    	The following list shows how many cards each player gets and how many to turn over at the start of the game based on the number of players:
    </p>
    <table width="200" border="0">
      <tr>
        <td align="center">Players</td>
        <td align="center">Cards</td>
        <td align="center">Turn Over</td>
      </tr>
      <tr>
        <td align="center"> 1</td>
        <td align="center">16</td>
        <td align="center">6</td>
      </tr>
      <tr>
        <td align="center">2</td>
        <td align="center">12</td>
        <td align="center">5</td>
      </tr>
      <tr>
        <td align="center">3</td>
        <td align="center">10</td>
        <td align="center">4</td>
      </tr>
      <tr>
        <td align="center">4</td>
        <td align="center">8</td>
        <td align="center">3</td>
      </tr>
    </table>
    <p>&nbsp;</p>
    <p>The game begins with Player 1 and continues with Player 2, and so on.
   	At the beginning of the game, each player turns any combination of 40% their cards face-up. (The exact number is in the table above.)  During each subsequent turn, the player must choose to 
   	draw a card from either the top of the deck or the discard pile.  If the player selects to pick a card from the deck, it is turned face-up and remains 
   	on the deck until he/she selects where to put it. The player can choose to replace any one of the card already in the hand by tapping that card, or to 
   	discard it by tapping the discard pile. If the player selects to pick the card atop the discard pile, he/she then taps the card in the hand to replace. 
   	When a player replaces a card in their hand, the new card is set face-up and the card previously in their hand is placed face-up on the discard pile. 
   	After this, the current player's turn is over and the next player's turn begins. This repeats until an end game scenario is reached. Read about how the game ends 
   	<a href="#end">here</a>.</p>
    <p>&nbsp;</p>
    <h2 id="score">Scoring</h2>
    <p>
    	The cards are scored in vertical pairs rewarding similar pairs.  The following matrix shows how pairs are scored:</p>
    <p><img src="images/score_matrix.png" width="787" height="498" alt="scoring matrix" /></p>
    
    <h2 id="end">End Game</h2>
    <p>
    	The game can end in two situations.
        First, if one player turns all of his/her cards face up, each player gets one  more turn, then ending the game.
    </p>
    <p>    
    	The other way to end the game is when a player taps their "Knock" button which can be used at any time in the game.  
    	When a player knocks, each player gets one more turn, then the game is scored.  If the knocking player does not have the highest score after the others;
        last turn, his/her score is halved. 
    </p>
    <p>    
        The player with the highest score is the winner.
    </p>
    <h2 id ="credits">Credits</h2>
    <p>
    	Developers:<br>
    	Eric Augustine<br>
    	Jim Jensen<br>
    	Spencer Vanderpoel<br>
    	Corban McCammon<br>
    	Brett Penza<br>
    	<br>
    	Game Designer:<br>
    	Dr. Robert Barber<br>
    	<br>
    	Game Specifications:<br>
    	The game specifications used for development are available <a href="http://www.bioone.org/doi/full/10.1662/0002-7685%282007%2969%5B359%3AAGITBS%5D2.0.CO%3B2">here</a>.<br>
    </p>
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